| Title | Origins and functions of the chlamydial inclusion. |
| Publication Type | Journal Article |
| Year of Publication | 1997 |
| Authors | Hackstadt, T, Fischer, ER, Scidmore, MA, Rockey, DD, Heinzen, RA |
| Journal | Trends in microbiology |
| Volume | 5 |
| Issue | 7 |
| Pagination | 288-93 |
| Date Published | 1997 Jul |
| Keywords | Biological, Models |
| Abstract | Chlamydiae dissociate themselves from the endocytic pathway shortly after internalization by actively modifying the vacuole to become fusogenic with sphingomyelin-containing exocytic vesicles. Interaction with this secretory pathway appears to provide a pathogenic mechanism that allows chlamydiae to establish themselves in a site that is not destined to fuse with lysosomes.
|
| DOI | 10.1016/S0966-842X(97)01061-5 |